This investigation was carried out during 2014 and 2015 seasons on nine years-old of Le conte pear trees budded on petchefolia rootstock to evaluate the effect of spraying trees with GA₃ or GA₄₊₇ at 20 ppm once at full bloom or twice at full bloom and after fruit set on fruit anatomical characteristics, fruit set, yield and fruit quality of Le conte pear trees. The current results revealed that spraying trees with GA₃ or GA₄₊₇ induced an increase in the number of cells in mesocarp which may be considered as indicator for finial fruit weight. Moreover, sprayed trees with GA₄₊₇ twice at full bloom and after fruit set led to an increase in average fruit weight more than those sprayed with GA₃ or GA₄₊₇ once at full bloom. Also, sprayed Le conte trees with GA₃ or GA₄₊₇ significantly increased fruit set, number of fruits and yield/tree as compared to the untreated one. Furthermore, sprayed trees with GA₄₊₇ at 20 ppm at full bloom and after fruit set gave a higher pronounced effect in this respect. Consequently, sprayed trees with GA₃ or GA₄₊₇ gave a higher values of fruit firmness, total acidity but reduced the values of SSC and SSC/acid ratio in fruit juice as compared to the control.