Two field experiments were carried out at the Farm of Rice Research and Training Center (RRTC),  Sakha, Kafr El-Sheikh, Egypt during 2013and 2014 seasons to study the effect of organic and inorganic fertilizer on growth, yield and its components of two rice cultivars. The experimental design was split-split plots with four replication , the two rice cultivars namely Giza177 and Giza178 allocated in the main plots , while fertilizer treatments i.e. N-levels  (0,120 and 165 kg N/ha )were applied in the sub plots and FYM ,P ,K and their combination devoted in the sub-sub plots . The main results revealed that Giza178cultivar  surpassed  Giza 177 cultivar in number of tillers hill^-1 ,leaf area index , dry matter accumulation content (g hill^-1)  ,number of panicles hill^-1 panicle length(cm) ,panicle weight(g) ,number of grains panicle^-1, grain and straw yield (t ha^-1) , while Giza177 produced highest 1000-grain weight . Plants treated with 165 kg N/ha gave the heights value of all growth character and yield component. Farmyard manure plus phosphorus plus potassium increased the previously mentioned characters. Also, application of FYM+P+K combined with either 120 or 165 kg N/ha produced higher yield than application only P+K combined with 120 or 165 kg N/ha . It means that adding FYM with 120 or 165 kg N/ha caused on increased in yield.