Laboratory experiments were conducted at the laboratory of Seed Technology Research Section, Mansoura during 2013 and 2014 years to study the effect of soaking wheat seed of. Misr 1, Misr 2 and Gemmiza 10 cultivars in six salty solutions i.e. CaCl₂  2%, CaCl₂   4%, KH₂PO₄ 1%, KH₂PO₄  2 %,KCL 2 %, KCL 4% and in addition to water and dry seed on germination percentage, seed and seedling vigor as well as seedlings chemical measurements under salinity conditions (0, 5 and 10 dS/m). The results revealed that: Increasing salinity levels not only reduced seed germination but also decreased seed vigor measurements which measured by (speed germination index, germination rate and co-efficient of germination). Seedlings measurements at the highest salinity levels (10 dS/m) were most weakness comparing (0 and 5 dS/m). Cholorophll a , b, carotenoids , K⁺ content and K/ Na ratio decreased at high salinity levels. Misr 2 wheat cultivar showed superiority and recorded the highest values of water uptake %, seed and seedling vigor, chemical measurements and lowest Na ⁺content .While, Gemmiza 10 wheat cultivar was the lowest  of all studied measurements and the highest of  Na ⁺  content. The highest values of seed, seedling vigor, chemical measurements (cholorophll a, b, carotenoids, K⁺ contents, and K/Na ratio) and lowest Na⁺ content in seedlings were obtained by wheat priming in KH₂PO₄ 1%solution.  In general, under salinity conditions, It could advised sowing seed of Misr 2 wheat cultivar and treated with KH₂PO₄ 1%solution to improved seed germination, seedlings vigor and mitigation the harmful effect of salinity according to the obtained results in this investigation.