Two field experiments were conducted at the Experimental Station Farm, Faculty of Agriculture, Mansoura University, Egypt, during summer seasons of 2015 and 2016 to study the effect of three irrigation intervals (10, 15 and 20 days) and five antitranspirants as a foliar application (Control, Kaolin, Jojoba oil, Glycerol and Green miracle) on two cultivars of eggplant (long white and long black) and their interactions on vegetative growth, yield and fruits quality. Obtained data revealed that long blackcultivar gave significantly increases in vegetative growth parameters, in the contrary; concerning number of fruits/plant, early yield, total yield and quality parameters i.e. crude protein in the first season and crude fiber in both seasons; long white cultivar was more superior with significant differences. Moreover irrigation intervals every 10 days gave significant increments in vegetative growth, yield and its component, while quality determinations values i.e. crude protein, total carbohydrates, crude fiber and vitamin c were increased significantly when irrigation intervals were every 15 days. Concerning foliar application treatments, jojoba oil spraying gave significant superiority comparing to other spraying treatments in vegetative growth measurements, yield and its components while green miracle produced the highest significant values of quality parameters i.e. crude protein, total carbohydrates, crude fiber and vitamin C. It could be recommended that using antitranspirants would improve eggplant cultivars productivity and quality under prolongation of irrigation intervals (every 15 days) especially in the dry hot weather.