The two field experiments were conducted during 2015 and 2016 seasons at the Experimental Farm of Rice Research Department (RRD), Sakha, Kafrelsheikh, Egypt. In order to examine the response of Egyptian hybrid rice one cultivar to foliar application of zinc sulphate, potassium sulphate and magnesium silicate. A randomized complete block design (R.C.B.D.) with four replications was used in the two seasons. The used treatments of foliar applications of zinc sulphate, potassium sulphate and magnesium silicate were used as follows: (T₁)_, control (without any application of the three tested compounds); (T₂), Zinc sulphate; (T₃), potassium sulphate; (T₄), magnesium silicate; (T₅), Zinc sulphate + potassium sulphate; (T₆),Zinc sulphate + magnesium silicate; (T₇), potassium sulphate + magnesium silicate and (T₈), Zinc sulphate + potassium sulphate + magnesium silicate. The foliar applications treatments were applied twice with the same concentration 2% at 15 and 30 days after transplanting. The studied characters were; plant height (cm), leaf area index, dry matter accumulation (g/m²), chlorophyll content in flag leaf ( SPAD-Value), number of tillers per m², number of panicles per m², number of grains per panicle, panicle weight (g), filled grain percentage, thousand grain weight, grain yield(ton/ha) and hulling, milling, head rice and milled grain protein percentages. The results showed that combined foliar application of the three tested compounds caused an increased in the previous studied growth characters, yield, yield attributes and grain quality of the Egyptian hybrid rice one cultivar. While, control treatment (without spraying) resulted maximum thousand grain weight (g) without significant differences between control and combined application of the three tested compounds in this criteria. All the other parameters showed overlapping results of different foliar application treatments.   According to the previous results, it could be concluded and that:  Using foliar application of zinc sulphate, potassium sulphate and magnesium silicate twice with the same concentration 2.0% at (15 and 30 days after transplanting) was the best treatment for obtaining the greatest grain yield besides improving growth and the grain quality of Egyptian hybrid rice one cultivar.   Using of the previous fertilizer compounds as foliar spray saved about more than two thirds from the amount of zinc sulphate and potassium sulphate if applied as basal application which is a result to application of magnesium silicate which caused integration with zinc sulphate and potassium sulphate.