To study the influence of foliar applications, N-levels and their interaction on growth, yield and its attributes and grain quality of barley Giza 123 cultivar, a field experiments was carried out at the Experimental Farm of Sahl El-Husseiniya, Agriculture Research Station, as a new reclaimed soils (salinity affected soils), during 2015/2016 and 2016/2017 seasons using design of strip-plot with 4 replicates. Vertical plots devoted to five foliar applications i.e. without, spraying with; Macro + Micro, amino acids, humic acid and the combination of Macro + Micro, amino acids and humic acid. Horizontal plots billed to 3 levels of N-fertilizer (40, 60 and 80 kg N/fed). Spraying barley plants with the combination of (Macro + Micro), amino acids and humic acid at the rates of 2 g + 1 ml + 1.25 ml/liter water, respectively in each spraying was the best treatment to increase barley growth, productivity and grains quality, which produced the highest values of these characters, with exception of total carbohydrates % in grains, which had inverse trend into both seasons. Fertilizing plants of barley with 80 kg N per fed gave the uppermost mean values of barley growth, productivity and quality of grains, except carbohydrates % in grains in together seasons. Foliar spraying barley Giza 123 cultivar with Macro + Micro, amino acids and humic acid at the side of fertilizing by 60 kg N per fed in order to maintain high productivity and grains quality and decrease production costs and environmental pollution under salinity affected soils conditions.