Two winter seasons experiment was conducted in 2013 - 2014 and 2014 - 2015 at Vegetable Research Farm, Fac. of Agric., MansouraUniv. to investigate phosphorus and potassium impact on growth and yield of cauliflower. The lay out of the experiments were factorial in the complete randomize block design with three replicates. The main plots were phosphorus (i.e.; 45, 60, 75 and 90 kg as P₂O₅ /fed.). The sub – plots were potassium (i.e. 30, 45 and 60 kg as K₂O /fed.). The data cleared that vegetative growth characters (i.e.; plant height, leaf area, weight of fresh leaves and leaves dry matter %), leaves chemical component (i.e., chlorophyll a, chlorophyll b, carotenoids, N, P and K). Curds yield and its physical quality attributes (i.e.; weight, diameter, compactness index, dry matter % and non- burst), curds chemical quality attributes (i.e.; Vitamin C, TSS, N, P and K) were significantly influenced by the interaction between phosphorus and potassium levels in both seasons. On contrast, leaves number were not affected by the combination of phosphorus and potassium.The interaction between phosphorus at 75 kg P₂O₅ and potassium at 45 kg K₂O /fed. was the most effective combination, Since it achieved the highest leaf area, leaves fresh weight, chlorophyll a, chlorophyll b, carotenoids, curd weight, curd diameter, curd compactness index, curd dry matter %, curds yield /fed., Vitamin C, TSS and N % of curd in both seasons. On the contrary, phosphorus at 45 kg P₂O₅ and potassium at 30 kg K₂O gave the lowest values of curd yield and quality parameters. Hence phosphorus at 75 kg P₂O₅ and potassium at 45 kg K₂O /fed.. is recommended to attain optimum curd yield and its component of cauliflower in the study area and other similar condition.