Two field experiments were conducted at the farm of Sakha Research Station, Kafr el-sheikh, Egypt in 2016 and 2017 rice seasons to study the performance of some rice genotypes under both different plant spaces and various nitrogen levels. Rice varieties i.e. SP70 (Sakha108), GZ9461, GZ7112 and GZ9057 (Giza 179) were used and cultivated under three spaces namely 15x20, 20x20 and 25x20 cm with three nitrogen levels i.e. control (without N-application), 110 and 165 kg N/ha. Statistical design of the experiment was split-split plot design. Rice varieties were applied in the main plots and plant space was allocated in the sub plots, while sub sub plots received nitrogen levels. The studied characters such as chlorophyll content, plant height, number of tillers and panicles, panicle length, panicle weight, 1000-grain weight, grain and straw yield were estimated. The main results revealed that the different genotypes slightly differed in their characters under study according to genetic background. The space of 25x20 cm was the best for all the studied characters of the tested genotypes except panicle length which responded to medium space 20x20 cm. The narrowing space of 15x20 cm was not suitable for all the genotypes and decreased most of the studied characters. The application of 165 kg N/ha caused an increased in the growth, yield attributes and grain plus straw yield. Results also indicated that the combination of wider space 25x20 cm with 165 Kg N/ha caused as a significant increase in all the previously mentioned characters expect 1000-grain weight which reached to its maximum value under both narrowing space 15x20 cm and control treatment (without N-application). The combination of all the genotypes under study with the space of 25x20 cm and 165 kg N/ha produced the same greatest grain yield except GZ7112 which gave the least. Straw yield of all the genotypes was nearly the same under both medium space (20x20cm) and narrowing space 15x20cm when fertilized by 165 kg N/ha specially GZ9057 which produced the highest straw yield under the same space and level of nitrogen.