The present study was conducted at Shandaweel Agricultural Research Station, Sohag Governorate [26.5013° N, 31.7651° E] during 2015/2016 and 2016/2017 seasons to investigate the effect of three ridge widths (80, 100 and 120 cm), two seeding rates (37800 and 50400 buds/fed) and three nitrogen levels (180, 200 and 220 kg N/fed) on yield and quality of sugar cane. Each experiment was carried out in split-split plot design with three replications. The results showed that planting sugarcane on ridges width at 100 cm apart attained a significant increase in cane stalk height, number of millable canes, cane yield/fed, as well as brix, sucrose, sugar recovery percentages and sugar yield/fed compared with those planted at 80 and 120 cm. Significant increase in stalk diameter was recorded at 120 cm ridge width in both seasons. The results indicated that the two seeding rates differed significantly in cane stalk height, stalk diameter, number of millable canes, cane and sugar yields, as well as brix, sucrose percentages in both seasons. Raising N fertilizer rate from 180 to 220 kg N/fed resulted in a significant increase in cane stalk height, stalk diameter, number of millable canes, cane and sugar yields /fed in both seasons. The results indicated that the interaction effect between ridge width of 100 cm, seeding rates of two rows (16800 of three-budded cane cuttings/fed) and fertilized by 220 kg N/feddan gave the highest values of cane and sugar yield /feddan. Under conditions of the present investigation, growing promising sugarcane variety G. 2003-49 in rows of 100 cm apart with seeding rate of 2 rows of cane cuttings (50400 buds/fed) and fertilized with 220 kg N/fed can be recommended to get the maximum cane and sugar yields/fed.