The objective of this study was to evaluate some genotypes under well irrigated compared with water stress conditions. The important results were as follows. Analysis of variance due to line x tester and combining ability for yield and fiber quality were highly significant for most traits in both normal and water stress conditions. The variance due to general combining ability (GCA) was lower than specific combining ability (SCA) for all studied characters which, means that all traits controlled by non-additive gene action. Contribution due to line parents were greater than contribution due to testers in under stress condition.  Higher values were recorded in the parental genotypes Giza 67 for seed cotton yield/plant followed by Giza 86 and Giza 94, while highest seed cotton yield/plant and lint yield were recorded by the cross combination Giza 86 x Dandra followed by Minufy x Australy, Giza 96 x Dandra and Giza 67 x PimaS6 Under normal irrigation condition. On the other hand, seed cotton and lint yield/plant were consistently affected by water deficit. Fiber quality properties were decreased in inferior direction except micronaire value, since fiber was relatively fine but it was weak and shorter under water deficit condition. Positive correlations between yield and each of its components were observed in most cases, while correlations among yield traits were higher in normal irrigation as compared with water stress.  Boll weight was positive correlated with most yield components at genotypic and phenotypic levels in both normal irrigation and water stress conditions.  Positive  correlation  in  general  were  found  between  most  fiber quality traits ( fiber strength (F.S), fiber length (F.L.) and fiber fineness (F.F.)) ,while it was positive between them with micronaire reading.