The effects of some cryoprotectants agents using sodium hexametaphosphate (SHMP), sodium tripolyphosphate (STPP), chitosan and xanthan on the chemical composition, physicochemical, microbiological and sensory quality properties of some marine fish species namely threadfin bream(Nemipterus furcosus), goldband goatfish (Upeneus moluccensis), marbled spinefoot (Siganus rivulatus) and gilt-head sea bream (Sparus aurata) collected from Mediterranean Sea during December 2020 were examined. The results showed that, the moisture, protein, lipid and ash of threadfin breams, goldband goatfish, marblede spinefoot and gilt-head sea bream fish species were (77.16, 75.13, 78.09, 76.81%); (19.68, 19.90, 18.08, 19.71%); (2.25, 2.45, 2.77, 2.52%) and (1.38, 1.65, 1.78, 1.08%), respectively. While the pH, TVB-N, TMA and TBA values of the examined fish species were ranged from (6.05 to 6.60); (15.12 to 19.35, mg/100g); (0.45 to 0.68 mg/100g) and (0.48 to 0.82 mg MDA/kg), respectively. Total bacterial count and coliforms count values of the investigated fish species ranged from (5.214 to 5.701 log₁₀ cfu/g) and (3.00 to 4.477 log₁₀ cfu/g), respectively. The sensory properties of the treated fish samples were better than control group. In conclusion, cryoprotectants agents had a clear effects for improving the physicochemical, microbiological and sensory properties of the studied fish samples while, it had no differences in chemical composition. On the other hand, polyphosphate was the most effective agent followed by chitosan and xanthan, so phosphate treatment can be an alternative way to improve the quality of some marine fish species.