Low thermal processed semimodified foods (SMF) are of great nutritional and healthful sources for antioxidants (AO). To test this qualification, SMF has to be examined facing an upnormal or over optimal cholesterol challenge. A number of 60 aged rats have been grouped to fulfill this estimation. The ten animal groups were arranged to test a sort of building up multi various combination of antioxidant sources. The results showed that rats make an increment in final body weight during 45 days at that age according to dietary pattern used. Dietary intervention concurrently appeared with fat challenge. The best food ingredient intervention in controlling FBW was accomplished by SSFTl followed by SSFTh. Moreover, more positive changes in serum total cholesterol level were achieved at the end of trail for SSFC and SSFTh followed by SSFTl. Blood cholesterol reduction by either S, SS or SSF may in part due to higher plant protein content with high-quality amino acids. The total cholesterol level was decreased with supplementation of vitamin E and C, the food formulas mentioned before most probably have more vitamin C than the others. All treatment groups showed significant reduction in triglycerides levels through that period relative to the positive control. The parsley food fragment is devoted as the most effective potential agent against cholesterolemia followed in this concern with tomatos. Dietary protein level has also been shown to influence lipid metabolism. In brief, according to data, SS can be considered a good food fragment in HDL-C dietary therapy that may further improved by parsley, flaxseed and tomato addition. Lastly, the strongest action against  elevation of glucose in blood was recorded for SSF group followed by SSFTh group, assuming a powerful action in this concern to the combinations of soybean, sunflower and flaxseed in the presence of tomato. It is, to be always in mind that, lipidemia in most cases conjugates several degenerative diseases especially glycemia.