The economic policy requires deep understanding to the etiology of the deterioration of environment, due to pollution in order to estimate the costs of pollution. Accurate evaluation of the etiology of environmental deterioration is quite awkward, due to the highly complicated interaction between the ecosystem and human activities. Environmental pollution is a global catastrophe, that is directly related to scientific evolution. As well, it is defined as any physical, chemical, or, biological shift or even change that might lead to hazards to air, water and land or in other words, whatever that might be dramatically affecting human health and other living organisms. Moreover, it is responsible for a decline in the production process on an aggregate level, hence, massively hazarding economics. This study aims at incorporation of ecological aspects while planning economic strategies in almost all agricultural processes, especially those that are incriminated as non friendly to environment. In addition to, emphasizing the significance of disruptions of ecosystem and its impacts on the gross economic level. Furthermore, to estimate the share by which environmental deterioration affects economic development. The dilemma of environmental pollution in Egypt is because of neglecting and ignoring ecological aspects and considerations on handling agricultural plans, due to lack of integration of all involved members, and lack of a global consideration on making projects. Planning agricultural strategies must handle projects from an ecological point of view on planning macroeconomic strategies.   The basic objective of the study is evaluation the effect of using pesticides on cotton crops to estimate the cases of human and livestock intoxication The results of the study illustrates the number of livestock intoxication cases in Bilqas and Manzala. The total number of intoxication cases is 1 death due to intoxication 14 male intoxication, 1 female. This is the result for 4 villages, Since, the number of Dakahleya's villages is 445 villages, population is 4,223,655 of about 15% of national population, since, these villages represent all villages, and if these results is applied for the whole governerate for they all survive the same circumstances, cultivating cotton, and using pesticides of the same quality. Therefore, the intoxicated cases are about death: 111, males: 1557, females: 111 Therefore, the intoxicated cases are 0.037% of Dakaheleya's population. The total of 4 villages livestock is 55 animals, therefore each village has about 13.7 animal, as a result the Dakahleya's livestock may be assumed to be 5785. The average mortality rate/village in Dakahleya is 2.25. Assuming that all villages (445 village) use the same pesticides, at almost equal quantities, and qualities of pesticides. Therefore, the expected annual mortality rate is 1001 animal. Supposing that, the average price of each animal L.E. 1000. The expected Dakahleya's annual losses is estimated at about LE 1 million.