Applicability of compost tea, cyanobacterial strains of Anabaena cylindrica, Nostoc calcicola and their extracts for enhancing growth and productivity of wheat plant were tested under glass house conditions. Individual and mixture with doses of inorganic nitrogen were the main treatments of the presented work. Results indicated that all the tested treatments were varied significantly in their effects during the tested three growth phases of 60, 90 and 120 days from planting. Due to use of C₇₅TNANEAE (N 75 % + compost tea + Nostoc  calicola , Anabaena cylindrica and their extracts), highly significant increase in vegetative and yield growth parameters, chemical content and NPK content ( in shoot, root, straw and grains) were obtained. Biofertilizers treatments were found to have pronounced increase in the number of viable bacterial count and the N₂-fixing cyanobacteria in soil. So, utilization of the cyanobacterial inoculum which containing Anabaena cylindrica and Nostoc calcicola, their extracts and compost tea in the presence of 75% dose of N for enhancing growth and yield of wheat plant and reduce chemical fertilizers usage were recommended.