In this study, a pot experiment was carried out in the glass house of the farm at Faculty of Agriculture, Mansoura University, Mansoura, Egypt during the winter season of 2018 to study the effect of inoculation with cyanobacterial strain (Anabaena cylindrica), their extracts and compost tea as individual or mixture with doses of inorganic nitrogen on the growth and yield of wheat plant. Obtained results showed that all the treatments as N fertilization rates, compost tea,  Anabaena cylindrica and its extract addition in single treatment or mixed together on wheat plant through three growth stages (60, 90 and 120 days from planting) are investigation significantly (p ≤ 0.05) different from one to another. The results indicated that highly significant increase in vegetative/yield growth parameters of wheat, pigments and NPK content ( in shoot, root, straw and grain) with the treatment of C₇₅TA (N₇₅%+Compost Tea+Anabaena). Also, the biofertilization has a pronounced increase number for viable bacterial count was the highest (7.70 X10³CFU) with mixture inoculation under 100% nitrogen fertilization after 60 days compared to those recorded by the other treatments. Followed by 75% nitrogen fertilization and compost tea with Anabaena after 60 days. The N₂-fixing cyanobacteria found that the highest count was obtained with C₇₅TA after 90 days 3.74 X10³CFU which was near to 60 day 3.44 X10³CFU. The cyanobacteria, their extracts and compost tea have been saved the inorganic nitrogen application by 25% compare with recommended nitrogen application.