A set of six rice field inoculation trials was selected at  two  governorates in  Egypt  located at the Nile delta. These  study was conducted  to investigate the response yield components of  three Egyptian rice varieties (Sakha 101, Giza 177 and Giza 178)  to  inoculation  with three  bacterial strains ( Rhizobium leguminosarum bv. trifolli  (RH) strain E11,  Anabaena  sp. strain ERC102  and Pseudomonas stutzeri strain ERP1 )  and their combination in the  presence of  three  levels of nitrogen (48,96 and 144 kg N/ha.) . The results were obtained from means of yield parameters calculated all over the six experiments . The results show that increasing with  inoculation in paddy yield , straw yield(15.26 ton/ha.), harvest index rang is within 33.13% and agronomic N- use efficiency compared with non- inoculated  counterpart . The results of the agronomic N-use efficiency in the six experiments indicated that biofertilization  can benefit  grain  production and then  reduced agronomic N-use efficiency with increasing fertilizer-N doses. Finaly , the results concluded that the  inoculation with bio-agents can reduce the need for additional fertilizer-N application to achieve and consequently  higher grain yield.