Urinary tract infection (UTI) is one of the most common bacterial infections and Gram negative bacteria are among the most prevalent bacteria detected from UTI patients. E. coli is the most common organism causing both community as well as hospital acquired UTI. The  high  incidence  of  UTIs  in  the  general population,  the  potential  for  complications, and  the associated costs of treatments emphasize the importance  of  appropriate  antibiotic  therapy. The resistance rates of uropathogenic E. coli to various antibiotics have been reported as beta-lactams, trimoxazole, quinolones, gentamicin, amikacin, cefuroxime, nalidixic acid