Development of new varieties with high yield and adequate biochemical traits for manufacturing industries become the main objective of sweet potato breeding programs. Currently, a limited number of sweet potato varieties are available without specific varieties for industrial purposes. The introduction of new resources is considered one of the most important approaches for genetic improvement for this crop. A total of fifteen sweet potato clones in addition to local check variety “Mabruka" were grown in a field trial during 2015 to 2016 to identify the promising clones for yield and some biochemical traits mainly related to industrial purposes and bioethanol production. High values of genetic variance combined with moderate to high heritability 12 "> in broad sense for the majority of studied traits indicating the magnitude of genetic variation in the total phenotypic expression. Furthermore, high coefficient of genetic variation was found among the evaluated material for total carotenoid followed by ethanol potential with 71.61% and 37.24%, respectively. Regarding genotype x season interaction, factorial analysis revealed the different responses of the tested clones for environmental conditions. The correlation coefficient analysis revealed a negative insignificant correlation between root yield and dry matter (r = -0.123) while positive highly significant correlation was noted between dry matter content and both total starch and ethanol production, r = 0.795 and 0.891, respectively. The results indicated that sweet potato promising clones have range dry matter content from 23.20 % to 31%; dry yield from 3.729 to 4.212 t/fed and starch from 52.91 to 65g/100g based on dry weight. Two sweet potato promising clones, “Carriru v" and “T carro 1" have yield potential 16.09 and 13.63 t/fed., respectively and ethanol production between 1826.3 to 2210.4 L/fed. It could be recommended that releasing these clones through the national variety release system as industrial sweet potato varieties. The clone UFVJM-56 had the highest carotenoid content with attractive orange flesh color, protein and dry matter content more than the “Mabruka" local variety that could be used as fresh type or in food industries due to its high nutritional value.