The present investigation was conducted to study the combining ability through L x T design of experiment hybrids for agronomic and yield and its component traits under normal and saline soil conditions. Six CMS lines were crossed with seven restorer lines to produce 42 hybrids where they along with their parental lines were evaluated. The analysis of variance for combining ability revealed highly significant differences among CMS and restorer lines for all agronomic and yield and its studied characters except for grain yield (ton/fed) under both normal and saline soil conditions. Among the CMS lines; Pusa 6A and IR69625A while among the restorers, PR3 and Giza 178R are proved to be good combiners for the majority of the characters including yield, by exhibiting values for high GCA effects. Out of 42 hybrid rice combinations, the top five hybrids based on SCA effects for grain yield characters under saline soil conditions are IR68902A/Giza 182R, IR70368A/Giza 178R, IR69625A/PR2, Pusa 3A/GZ6296R and IR58025A/PR2.