In this study, the anticoccidial properties of micronized curcumin against Eimeria tenella in a comparison with the ordinary one were investigated. The experiment was conducted using 105 broiler chicks, divided into four groups; micronized curcumin (A), curcumin (B), infected untreated (C) and uninfected untreated (D). Group A and B were treated for seven successive days with micronized curcumin (with sodium alginate) and curcumin suspended in corn oil respectively. All Chicks were infected orally with E. tenella at the 22th days of age except the control negative one. Depending on the anticoccidial indices (relative weight gain, survival rate, lesion value and oocyst value), the micronized curcum in treated group showed a higher protection than curcumin treated. As anti-oxidant, both of curcumin treated groups revealed a significant increase in glutathione (GSH), superoxide dismutase (SOD) and catalase comparing with the control infected untreated group at p ≤ 0.05. In addition, significant decrease of malondialdehyde (MDA) concentration of treated groups comparing with infected untreated group was recorded (p≤0.05). Since curcumin had anti-inflammatory properties, TNFα and IL 10 βR were significantly decreased in curcumin treated in a comparison with the infected untreated groups at p ≤ 0.05. In conclusion, the micronized curcumin has a marked role in restricting the adverse effect of E. tenella infection in broiler chickens better than curcumin alone.