The present study aims to investigate the effects of orally quaffed antioxidant (as a source of vitamin E) throughout 7 weeks on growth performance, digestibility coefficient and carcass traits, hematological, and serum biochemical, and economic efficiency parameters of the growing black Balady rabbit males. Eighteen rabbits with an average body weight (436.75 ± 10.87 g) were randomly allotted into two experimental treatments as T₁ and T₂ (n=9; rabbits/treatment), which were individually subdivided into three replicates (n=3; rabbits/replicate). All rabbits in T₁ served as a control treatment and fed basal diet plus orally quaffed a dosage of coconut oil as a carrier material of vitamin E up to 2.0 mL / kg live body weight (LBW) / two times weekly. However, T₂ rabbits were fed the same basal diet and orally quaffed a dosage up to 2.0 mL of antioxidant (each mL contain 7 mg of vitamin E) / kg LBW/ two times weekly. The results cleared that, rabbits in T₂ significantly (P<0.05) enhanced all growth performance parameters, digestibility coefficient (%), nutritive values (%), carcass characteristics, and serum biochemical measurements compared to those in T₁. Oxidative capacity status was significantly improved in T₂ rabbits relative to T₁ rabbits. The economic efficiency and relative economic efficiency parameters were higher in T₂ than T₁ rabbits. Conclusively, orally using vitamin E as an antioxidant agent could be a useful tool for improving the productive performance, and physiological, and oxidative status parameters, besides its economic benefits for rearing native black Balady rabbits.