Total of thirty growing New Zealand White rabbits (NZW) aged 35 days and 624121.5(9) live body weight were used in this study. Rabbits were divided into similar three groups and treated once weekly as follows: The 15‘ group (control) was injected with saline solution, the 2““ and the 3" groups were treated by eltroxin (hyperthyroidism) and carbimazoie (hypothyroidism), respectively for two moths. At 12 weeks of age. feed intake, body weight and body gain in carbimazole treatment were higher than eltroxin and control. Also, it improved growth rate and feed conversion than control by 8% and 3%, respectively. At 12 weeks of age, the minimum rectal temperature was found in eltroxin group. Carblmazole had the higher final body weight than eltroxin and control by 11.1% and 135%. respectively. Dressing percentage was significantly (P<0.05) higher in eltroxin and carbimazole than that of the control group. However, weights of liver, kidneys, lungs and heart were almost higher in the control than both tested groups. Level of T4 and T3 in control group increased compared to hyperthyroidism or hypothyroidism. There is no hematological change in both hyper and hypothyroid groups.