This study aimed to find out the effect of feeding some locally available and cheep plants as lettuce and garden rocket on some biochemical parameters in normal rats. After feeding normal rats the experimental diet for 28 days. The results obtained showed a gradual increase of relative liver, kidney and spleen weight. Rats fed the experimental diets presented a gradual decrease of total blood and liver cholesterol, triglycerides, phospholipids, free fatty acids and HDL-cholesterol, also a gradual decrease of AST, ALT and ALP levels was obtained. Blood creatinine, urea and glucose levels were also decreased. A slight increase of serum calcium, phosphorus, magnesium, zinc, iron, ferritin, blood hemoglobin and hematocrit was observed in rats fed the experimental diets.