This study was carried out at three different buffalo experimental stations belonging to animal production research institute, ministry of agriculture, Egypt. The stations were located in different areas. The first station was Seds station located in Bani Sweif governorate at middle Egypt. It was adjacent to a high density traffic way.  The second station was Mehalet Mousa station located in Kafr El-Sheikh Governorate. It was 1.5 km away from a moderate density traffic way. The third station was Gemmeza station located in Gharbia governorate. It was 27 km far from a somewhat low density traffic way. The effect of environmental (traffic) pollution on components of milk and blood of buffalo was studied. Forty five adult lactating buffalo cows ranged from 4 to 10 years age, 380 to 770 kg weight and 1 to 6 parities. The highest level of lead in blood was found in Seds station (0.979ppm) followed by Mehallet Mousa (0.792ppm) and Gemmaza station (0.441ppm). Lead level in milk was significantly (P<0.05) higher in samples taken from Seds station than in Mehallet Mousa and Gemmaza stations (2.774 vs. 0.579 and 0.553ppm, respectively). Cadmium level in whole blood ranged from 0.006 to 0.08 ppm in the three stations. The highest level was in Seds station (0.034ppm) and the lowest one was in Gemmaza station (0.023ppm).  Cadmium level in milk ranged from 0.01 to 1.56ppm.The highest level was in Seds station (0.543 ppm), and the lowest level was in Gemmaza station (0.237ppm).  It could be concluded that the nearness of farm animals to traffic roads with high traffic density causes a rise in milk content of lead and cadmium.