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MODULATION OF PLASMA, BRAIN AND LIVER CHOLINESTRASES ACTIVITY; FATTY ACIDS PROFILE AND PERFORMANCE OF JAPANESE QUAIL BY A MEDICAL DRUG MIXTURE

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Last updated: 04 Jan 2025

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Abstract

A total of 120 one day old Japanese quail chicks were used in this experiment. During the first two weeks, all chicks were fed a diet formulated to meet the recommended requirements  for the growing quails. Thereafter, chicks were randomly classified into three equal groups (each of 40 chicks). The first and second groups, the treated groups were fed on the basal diet, supplemented with 3.3 and 6.6 mg/ kg /diet of a mixture, containing some chemical drugs i.e. Clidinum, Almitrine, Raubasine and Trazodone (CART), while the thirdgroup received only the basal diet whithout any addition (control). At four and six weeks post of groups, five quails from each of groups were randomly chosen and slaughtered. Plasma samples were collected and frozen until biochemical analysis. Liver and brain were frozen until estrases enzymes activities  were determined.
The achieved results indicated that body weight, feed consumption and feed efficiency and relative weight of some organs and plasma Cholinestrase activity during both of the two experimental periods of feeding have not been significantly affected by the CART supplementation. Lipogenic activity in liver slices (in vitro) was significantly affected by 6.6 mg CART and relatively by other groups, (9.33%) (control and 3.3 mg CART). Feeding CART increased liver ChE activity especially in quails  that fed on 6.6 mg than the other groups (47.7%) . Also, age of birds had a significant effect on liver fat content (3.7%). Brain AChE activity increased significantly especially in quails fed on 3.3 mg CART than other groups (22%). The CART feeding especially at the level of 3.3 mg increased unsaturated than saturated fatty acid in the liver fat. This study revealed that diets supplemented with CART possessed the ability to control the appetite center through different ways in regulating feeding intake and growth in quail birds.
A total of 120 one day old Japanese quail chicks were used in this experiment. During the first two weeks, all chicks were fed a diet formulated to meet the recommended requirements  for the growing quails. Thereafter, chicks were randomly classified into three equal groups (each of 40 chicks). The first and second groups, the treated groups were fed on the basal diet, supplemented with 3.3 and 6.6 mg/ kg /diet of a mixture, containing some chemical drugs i.e. Clidinum, Almitrine, Raubasine and Trazodone (CART), while the thirdgroup received only the basal diet whithout any addition (control). At four and six weeks post of groups, five quails from each of groups were randomly chosen and slaughtered. Plasma samples were collected and frozen until biochemical analysis. Liver and brain were frozen until estrases enzymes activities  were determined.
The achieved results indicated that body weight, feed consumption and feed efficiency and relative weight of some organs and plasma Cholinestrase activity during both of the two experimental periods of feeding have not been significantly affected by the CART supplementation. Lipogenic activity in liver slices (in vitro) was significantly affected by 6.6 mg CART and relatively by other groups, (9.33%) (control and 3.3 mg CART). Feeding CART increased liver ChE activity especially in quails  that fed on 6.6 mg than the other groups (47.7%) . Also, age of birds had a significant effect on liver fat content (3.7%). Brain AChE activity increased significantly especially in quails fed on 3.3 mg CART than other groups (22%). The CART feeding especially at the level of 3.3 mg increased unsaturated than saturated fatty acid in the liver fat. This study revealed that diets supplemented with CART possessed the ability to control the appetite center through different ways in regulating feeding intake and growth in quail birds.

DOI

10.21608/jappmu.2008.217995

Keywords

CART-Performances - Liver Lipogenic activity, Liver ChE activity - Fatty acids profiles- Brain AchE activity, Liver fat content

Authors

First Name

Nematallah

Last Name

Ali,

MiddleName

G. M.

Affiliation

Poultry Production Dept., Fac. Agric., Ain – Shams Univ., Cairo, Egypt.

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Orcid

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First Name

Hala

Last Name

Gamal El–Dein

MiddleName

M.

Affiliation

Poultry Nutrition, Biological and Environmental Dept., Faculty of Home Economic,. Al – Azhar Univ.

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City

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Orcid

-

First Name

Eman

Last Name

El- Daly

MiddleName

F.

Affiliation

Animal and Poultry Nutrition and Production Dept., National Res. Center. Dokki, Giza, Egypt.

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City

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Orcid

-

First Name

S.

Last Name

El-Damrawy

MiddleName

Z.

Affiliation

Animal Production Dept. Fac. Agric. Tanta Univ., Cairo, Egypt.

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Orcid

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Volume

33

Article Issue

5

Related Issue

31015

Issue Date

2008-05-01

Receive Date

2008-04-15

Publish Date

2008-05-01

Page Start

3,255

Page End

3,265

Print ISSN

2090-3642

Online ISSN

2090-3723

Link

https://jappmu.journals.ekb.eg/article_217995.html

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https://jappmu.journals.ekb.eg/service?article_code=217995

Order

7

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Original Article

Type Code

876

Publication Type

Journal

Publication Title

Journal of Animal and Poultry Production

Publication Link

https://jappmu.journals.ekb.eg/

MainTitle

MODULATION OF PLASMA, BRAIN AND LIVER CHOLINESTRASES ACTIVITY; FATTY ACIDS PROFILE AND PERFORMANCE OF JAPANESE QUAIL BY A MEDICAL DRUG MIXTURE

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Article

Created At

22 Jan 2023