Two hundred and ten unsexed one day old Cobb 500 broiler chicks were used until 6 weeks of age to study the effect of Trichoderma reesei fungus(10⁸ CFU /ml)and sodium hydroxide(NaOH, 10 g/kg OPM)addition in olive pulp meal(OPM)broiler diets on growth rate, digestion coefficients, some blood parameters, carcass traits and the economic efficiency of feed. The chicks were randomly distributed into seven equal treatments, 30 chicks/treatment with three replicates each. The treatments were control, C (The basal diet without OPM),T1(Basal diet+12% OPM),T2 (Basal diet +12% OPM+fungus), T3 (Basal diet+12% OPM+NaOH), T4 (Basal diet +15% OPM), T5 (Basal diet + 15% OPM + fungus) and T6 (Basal diet + 15% OPM + NaOH). The treated OPM with NaOH showed similar results of body weight and gain as the control .The control treatment recorded the highest value(P<0.01)of feed intake. The best value (P<0.05) of feed conversion ratio was noticed with T3. The treated OPM showed a significant (P<0.05) in CP, CF, NFE, DCP, TDN (%) and ME(kcal/kg)compared to the untreated OPM; The treated and untreated OPM increased plasma cholesterol, LDL and HDL levels, While Triglycerides were decreased with all treatments compared to the control. All treatments recorded high values (P<0.05) of gizzard (%), cecum weight and cecum length compared to the control, the treated and untreated OPM decreased the feed cost/kg meat and increased the net return/kg meat.The results concluded that treating OPM with NaOH or fungus improved the nutritive value of OPM without any adverse effects on birds.