The goal of this study was to see how dietary -glucan (BG) supplementation affected growth performance, blood biochemicals, and antioxidant capacity in growing NZWrabbits. 75 NZW rabbit females, 6 weeks old, with an average live body weight of 845.3735.23 g. Rabbits were distributed into five experimental groups at random (fifteen rabbits in each group). The control group (G1) received only the basal diet, while the G2, G3, G4, and G5 groups received the basal diet supplemented with BG at 0.5,1.0,1.5, and 2.0 g/kg diet, respectively. Growth performance parameters, blood biochemical, and antioxidant enzymes, and immunity markers in the hepatic tissues were determined. Results show that all BG supplements developed (P<0.05) final weight, and gain without any effects on feed efficiency, and viability, and decreased (P<0.05) concentration of glucose, total cholesterol, and triglycerides. The effect of BG on serum activity of ALT and AST was not significant. Dietary BG supplementation increased (P<0.05) SOD, CAT, and GPx levels, and decreased (P<0.05) MDA levels in hepatic tissues. Percentage of NBT and ACP level increased (P<0.05) BG groups (G2-G5) in comparing with G1.The current study concludes that β-glucans represent a promising factor for improving antioxidant capacity, immunity, and lipid profile as well as promoting growth performance of growing rabbits, without adverse effects on liver and kidney function and protein metabolism.