Thirty two newly born calves including 16 Friesian calves and 16 Baladi (8 males and 8 females) in each group. Breeds are assigned in two feeding regimes, equalized by breed, sex and birth weight and continued in a feeding trial during suckling period until reached weaning105 days as follows:Regime(I): 78.34% milk + 11.68% calf starter + 9.98% berseem hay, Regime(II): 72.49% milk + 19.62% calf starter + 7.89% berseem hay. Results showed that digestibilities of CF and EE were significantly higher (P<0.05), however digestibilities of DM, OM, NFE were significantly lower (P<0.05) in regime(I). Whereas, CP digestibility, TDN and DCP were nearly similar. Only ruminal TVFA's concentration was significantly higher (P<0.05) with increasing the amount of calf starter in regime(II) compared with regime(I). Whereas, ruminal pH and NH3-N concentration, all blood serum metabolites and intake of DM, TDN and DCP were nearly similar. WG, TWG, average DG and feed conversion ratio were higher significantly (P<0.05) for calves fed regime(II). However, weight gain output, net output and economic efficiency were higher significantly (P<0.05) in regime(II). Economic efficiency increased by 27.21 and 39.83% for regime II compared with regime(I). Feeding regime(II) improved average DG of Friesian and Baladi calves by 11.88 and 18.40%, respectively, which increased by 6.52% for Baladi calves than Friesian calves. Friesian calves revealed significantly (P<0.05) higher feed conversion ratio compared with Baladi calves. Economic efficiency increased by 13.84 and 22.18% for Friesian compared with Baladi calves. Whereas, there were no any significant differences between male and female calves.