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161171

Genetic Polymorphism of GH, IGF1 AND BMP15 Genes in Maraz Goat

Article

Last updated: 22 Jan 2023

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Abstract

The Studies of genetic polymorphism in local animals aim at evaluating the genetic diversity of animal breeds chiefly for conservation purposes. In this research, single nucleotide polymorphism (SNP) was used to detect point mutation of GH, IGF1, BMP15 genes in Maraz goat. Forty blood samples were collected from Maraz goat, DNA was isolated and primer was used to amplify GH, IGF1, and BMP15 genes. Finally, sequencing methodology was applied for PCR products. Results of GH gene showed only one SNPs (AG) at nucleotide number 58pb. The sequence results of IGF1 illustrated two point mutations at nucleotide number 5502 and 5675 bp. While according to data sequences no point mutation was detected of BMP15 gene. These outcomes revealed that the SNP marker of the GH, IGF-I, and BMP15 genes will be a possible molecular marker for growth traits and cashmere fiber in Maraz goat. This research displays that the genetic similarities between Maraz goat and other breeds match their geographical distribution which indicates that the Maraz goat is robustly separated from the other breeds.

DOI

10.21608/jappmu.2020.161171

Keywords

GH, IGF1, BMP15, SNPs, diversity, Maraz goat

Authors

First Name

Karwan

Last Name

Khan

MiddleName

Mohammad Hama

Affiliation

Animal Science department, College of Agricultural Engineering Sciences, University of Sulaimani, Sulaimani City, Kurdistan Region, Iraq

Email

karwan.hamakhan@univsul.edu.iq

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Orcid

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Volume

11

Article Issue

12

Related Issue

20344

Issue Date

2020-12-01

Receive Date

2021-04-05

Publish Date

2020-12-01

Page Start

503

Page End

507

Print ISSN

2090-3642

Online ISSN

2090-3723

Link

https://jappmu.journals.ekb.eg/article_161171.html

Detail API

https://jappmu.journals.ekb.eg/service?article_code=161171

Order

3

Type

Original Article

Type Code

876

Publication Type

Journal

Publication Title

Journal of Animal and Poultry Production

Publication Link

https://jappmu.journals.ekb.eg/

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Article

Created At

22 Jan 2023