A total number of 18 growing males of New Zealand White rabbits aged 5 weeks were randomly divided into 3 experimental groups to study the effects of using different forms of Nigella sativa as a replacement of soybean meal protein on growth performance, and economical efficiency of NZM rabbits. The rabbits of the control group was fed diet free from NS, replacement soybean meal protein by NSM protein was used at levels of 25% in the group (2) and Nigella sativa seed (4kg/tn) used in group (3). The experiment lasted for 60-70 day. The growth performance of the experimental rabbits was studied in terms of average weight gain through out the experimental period, also economical efficiency was calculated for all  the rabbits groups studied. The obtained results indicated that the highest values of body weight, body weight gain, and economical efficiency were observed for groups fed Nigella sativa meal and seed at the end of the experiment, followed by control group. The results showed that NSM protein can be used in rabbits diets up to 25 % of soybean meal protein during growing period without any adverse effect on performance.