To study the effect of dietary inclusion of graded levels (0, 1 and 2 %) of Cresson seed meal on Nile tilapia fry performance, a feeding experiment in plastic tanks was conducted in a wet lab. for 16 weeks. The obtained results revealed improving effect of this feed additive (Cresson seed meal, particularly at 1 %) on fish relative growth rate, its feed utilization (feed protein intake, protein productive value, protein efficiency ratio, energy retention). Also, fish carcass ether extract and energy content had increased by this treatment; so, it could be recommend the dietary inclusion of 1 % Cresson seed meal to improve Nile tilapia growth and feed utilization.