A total of 4257 lactation records of 1031 buffaloes in 5 herds were recorded by the Cattle Information System/Egypt (CISE) of the Faculty of Agriculture, Cairo University during the period from 2005 to 2011.  The overall averages of of lactation period (LP, day) ,total milk yield (TMY, kg),  and daily milk yield (DMY ,kg) of buffaloes were 269 days, 1854 kg and 6.9 kg , respectively . All effect of farm , season , parity , enrollment interval and interaction between farm and enrollment interval were significant (P<0.0001) on all traits studied. Continuation of enrollment increased improvement in TMY and DMY. The highest TMY and DMY was recorded for the longest enrollment period from 2005 to 2011 (1943 and 7.23 kg , respectively). The results indicated that enrollment in the CISE program for milk recording would increase TMY and DMY of Egyptian buffalo, the longer the enrollment interval the higher the increase of both TMY and DMY.