A total of 1600 lactation record during the years 2000 to 2007 were collected to represent 554 cows were inseminated 84 sire in Alkarda station in Kafr El-Sheikh of the Institute of Animal Production Research, Agricultural Research Center, Egypt . The objective of this study was to estimate the genetic and non-genetic parameters, breeding value (BV) for some productive and reproductive traits, determine economic values for various production traits total milk yield (TMY), lactation period (LP),calving interval(CI) and dry period (DP) in dairy production, as well as to determine total economic selection index. The research is based on data which include 1600 lactations of 554 cows. Data were collected during the period 2000 – 2007. The derivative-free restricted maximum likelihood (REML) procedure was used to determine heritability, genetic correlation and breeding value of the studied traits. It was determined that within economic selection index the most important trait is milk yield, while values for other traits are almost negligible. Selection indices using one phenotypic standard deviation as REV1 and limit method as REV2. The results indicated that non genetic factors affecting (TMY), (LP), (CI),(DP) and interaction between (parity & season), (parity& year ), (year & season) had highly significant (p<0.001) effect on those traits except the effect of CI and DP . The overall means (Mean) of TMY, LP, GI and DP were 3158.8 kg; 343.5, 453.9 and 78.5 day, respectively. Heritability estimate (h2) for TMY, LP, GI and DP were 0.33, 0.08, 0.07 and 0.04, respectively. Phenotypic correlation between each two traits ranged from -0.11 to 0.29; and genetic correlation between each two traits ranged from -0.29 to +1 . Ranges estimates breeding values(BV) of cows estimated for TMY, LP,GI and DP were 1034.8, 522.5, 223.6 and 46.5, respectively in herd which was higher than those for sire 573.8, 152.4,127.9 and 19.6 and those fore dam 1034.8, 445.2, 154.3 and 29.8, respectively. general indices I1 and I12 incorporating TMY, LP, GI and DP was the best (RIH = 0.63) and it is recommended if the selection was exercised; in addition there are high similarity of genetic gains under the two different groups of economic values REV1 and REV2.General guide was the most efficient use of my way to derive economic value I1 = 0.36216 (TMY) -0.77931 (LP) + 0.83967 (CI) - 3.96728 (DP). I12 = 0.34412 (TMY) - 0.46265 (LP) + 0.34458 (CI) - 1.12974 (DP). This study will help the breeders to select the best dairy animals which will be used for production. The future generations based on genetics of milk production and reproduction traits in early lactation.