At 135 days of gestation, twenty Zaraibi does (42.67±1.35 kg BW) were allotted into two dietary groups of 10 each to study glucogenic supplementation impact on feed intake, some blood parameters and productive performance of transition Zaraibi goats. Animals divided according to their body weight, parity and milk production in previous season. Control does (CON) received a diet without supplementation, whereas in treated group a solid feed supplement rich in glucogenic substances, colloidal silica and organic cobalt was used namely glucogenic mixture (GM) supplementation. The GM contained mainly of three major glucogenic additives (glycerin, propylene glycol and calcium propionate). The GM was incorporated daily as a rate of 50 g/head/d. The trial period lasted for 6 weeks, (2 weeks pre-parturition and 4 weeks post-parturition). Blood samples were collected week before parturition and week post-parturition for hematological and biochemical estimations. Milk yield was measured biweekly for each doe and milk samples were taken. Results revealed that the feed intake in terms of total DM was not clearly affected as compared between GM supplementation and control groups. With supplementing does the blood triglyceride, AST, ALT, β-hydroxybutyrate and cholesterol concentrations were significantly decreased. Higher significant concentrations of glucose, insulin and thyroid hormones were detected in supplemented group. Moreover, supplementing the does with GM improved most of tested blood hematological parameters during the transition period. Additionally, heavier weights of kids at birth, at 15 and 30 d of age were obtained, as well as no kids' mortality cases were recorded by supplementing does with GM. The GM supplementation resulted in about 15.89 and 16.43 % increases in daily milk yield at 15 and 30 days of does' lactation, respectively. At 30 days of lactation, supplemented group showed significantly higher milk fat, protein, ash and total solids percentages. Furthermore, as a result of GM supplementation the economic efficiency value was noticeably higher. The results demonstrated thatglucogenic mixture supplementation not only supply sufficient energy, but also improve the general health status and milk yield of dairy Zaraibi does as well as modify the composition of their milk.