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265490

COMPARISON BETWEEN PICSI AND ICSI AND ITS EFFECT ON BLASTOCYST FORMATION, A PROSPECTIVE RANDOMIZED TRIAL.

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Last updated: 04 Jan 2025

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Abstract

Although ICSI may not provide a significant advantage over in vitro fertilization (IVF) in cases of non-male factor infertility, it is recommended to for search another method to increase the baby take-home rate in Assisted Technology. To assess the efficacy of two ready-to-use systems: intracytoplasmic sperm injection (ICSI) and Physiological intracytoplasmic sperm injection (PICSI) in a randomized manner on embryo development and blastocyst formation. This study was designed as a prospective, randomized trial. Couples receiving an ICSI or PICSI treatments with fresh embryo transfer were enrolled in this parallel two-groups, randomized trial. The study included 100 infertile women. Their age was between 25 to 39 years. Freshly ejaculated sperms for the treatment after at least 3 days of sexual abstinence. Couples were randomly randomized (1:1) to receive either PICSI or a standard ICSI procedure.PICSI and ICSI showed no statistically significant difference as regards fertilization rate, implantation rate and embryo transfer rate but showed statistically significant in blastocyst formation, clinical pregnancy and pregnancy continuation.
Conclusively, according to these findings, the PICSI technique had a higher chance of achieving pregnancy than the ICSI technique.As a result, the approach is preferable to be used in laboratory routine work than ICSI to avoid the selection of immature sperm, which leads to increased clinical pregnancy in male factor infertility, especially with DNA fragmentation. To back up this claim, prospective and randomized trials should be used.
399

DOI

10.21608/jpd.2022.265490

Keywords

ICSI, PICSI, blastocyst formation, Pregnancy

Authors

First Name

Ayat

Last Name

samir

MiddleName

-

Affiliation

Department of Animal Biotechnology, Genetic Engineering and Biotechnology Research Institute, University of Sadat City, Sadat City, Egypt

Email

ayasamer@yahoo.com

City

University of Sadat City, Sadat City, Egypt

Orcid

-

First Name

Momen

Last Name

Kamel

MiddleName

-

Affiliation

Department of Obstetrics and Gynecology, Faculty of Medicine, Assuit University, Egypt.

Email

-

City

Faculty of Medicine, Assuit University, Egypt

Orcid

-

First Name

Bahget

Last Name

Elfeky

MiddleName

-

Affiliation

Department of Animal Biotechnology, Genetic Engineering and Biotechnology Research Institute, University of Sadat City, Sadat City, Egypt.

Email

-

City

Research Institute, University of Sadat City, Sadat City, Egypt.

Orcid

-

Volume

27

Article Issue

3

Related Issue

28819

Issue Date

2022-07-01

Receive Date

2022-05-15

Publish Date

2022-07-01

Page Start

399

Page End

415

Print ISSN

1110-2543

Online ISSN

2682-3322

Article File

JPD_Volume 27_Issue 3_Pages 399-415.pdf

PDF . 729.3kB

Link

https://jpd.journals.ekb.eg/article_265490.html

Detail API

https://jpd.journals.ekb.eg/service?article_code=265490

Order

4

Type

Original Article

Type Code

867

Publication Type

Journal

Publication Title

Journal of Productivity and Development

Publication Link

https://jpd.journals.ekb.eg/

MainTitle

COMPARISON BETWEEN PICSI AND ICSI AND ITS EFFECT ON BLASTOCYST FORMATION, A PROSPECTIVE RANDOMIZED TRIAL.

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Article

Created At

22 Jan 2023