Background: Employees' corrupt behaviors can be justified by citing organizational customs, values, and obligations. As a result, a true culture, justice, and devotion are important in any agency. Aim:Investigate the relationship among organizational corruption, culture, justice, and nurses' attitude towards work at Zagazig University Hospitals (ZUH,s), Egypt. Subjects and method: Design: A descriptive correlational design was adopted for this study. Setting:? Subjects: A stratified random sample (n=377) of nurses from different classifications was selected.  Tools: Data was collected using four tools,Organizational Corruption Scale, Organizational Culture Inventory, Organizational Justice Scale, andNurses' Attitude towards Work (Organizational Commitment type) Scale. Results:Revealed that, 72.5% of nurses reported that corruption practices occurred inside ZUH's. Likewise, 74.8%,& 71% of nurses had a positive perception of organizational culture and justice and only 75.3% of them had a high level of attitude toward work. Conclusion: Corruption was negatively associated with organizational culture, justice, and nurses' attitude towards work. Also, organizational culture, justice, and attitude toward work predicted the presence of corrupt practices. Recommendations: Authorities and nursing leaders must take a variety of steps to fight corruption, including enforcing policies and regulations, establishing an anti-corruption committee, systems for controlling, punishing transgressors, and rewarding honest conduct.