Background:  Chronic limb-threatening ischemia (CLTI) is linked to a lower quality of life chronic limb ischemia represents the end stage of peripheral arterial disease and is associated with a high risk of limb amputation. Aim: To assess health needs of patients with chronic lower limbs ischemia in general Port Said hospitals. Subjects and method: Design: Descriptive research design was used in the study. Setting: The study was conducted at surgical, diabetic outpatient clinics at El Mabara hospital), Due to renovation on building in other hospitals. Subjects: A convenient sample of eighty male and female patients who diagnosed with chronic lower limbs ischemia were included. Tools: Data werecollectedusing three tools, Tool I patients assessment questionnaire Tool II Patients physical examination Tool III patients health needs questionnaire. Results: The result of study indicated that 64.5% had inadequate leg exercise, 67.5% had unsatisfactory foot care and 82.5% had unhealthy diet. Conclusion: most of studied patients had inadequate exercise, unsatisfactory foot care and unhealthy diet Recommendations: There are clear requirements for conducting health education about exercise, importance of foot care and having a healthy diet.