Background: Cesarean delivery is associated with increased maternal risks such as puerperal infection, hemorrhage, thromboembolism and death. Despite the gross increase in caesarean section rate, there is still high perinatal mortality.         Aim: The aim of the study was to determine the effect of nursing intervention guidelines for women undergoing cesarean section on the occurrence of postoperative complication.        Materials and Methods: The study was carried out in the obstetric and gynecological departments in Port Said Hospitals using a quasi-experimental study design. This study was carried out in the obstetric and gynecological department at three governmental hospitals located in Port Said city: Port Said general hospital, Port Fouad hospital and El-tadamon hospital. The sample constituted 250women; the study subjects were divided into two equal groups of 125 parturient women each, as follows: Group A; the study group, who receive postoperative care program. Group B; the control group who receive postoperative routine hospital care after cesarean section. Data were collected using four tools devised specifically for the study.      Results: Women in the study group had lesser percentages of danger signals that denote wound infection than the control group. Majority of women in the study group had mild pain grade in the third day after the operation compared to the control group. The overall incidence of wound complication was higher in the control group than the study group. There was a statistically significant difference between the study and control groups in favor of the former regarding; sub-involution of the uterus, secondary PPH, breast problems In addition to DVT, abdominal distention, constipation        Conclusion: The majority of women in the study group had mild pain grade in the third day after the operation compared to the control group. Incidence of wound complication was higher in the control group than the study group.