Background: Nausea and vomiting during pregnancy (NVP) is the first and most frequently reported minor discomforts during early pregnancy. Ginger is alternative therapy used for pregnant women with NVP. Aim of the study: The aim of the study was to evaluate the effect of ginger versus antiemetics on relieving mild to moderate morning sickness among pregnant women. Design: quasi – experimental design was adopted in this study.  Setting: the study was carried out at the obstetrics outpatient's clinic in Suez Canal University hospital in Ismailia city. Sample: Purposive sampling was used to recruit 100 pregnant women have NVP during the first trimester of pregnancy. 50 women were assigned into study group (those who undergo use ginger syrup 1 gm per day for four consecutive days), and other 50 women were assigned as control group. Tools and procedure: Structure interviewing schedule, and McGill Nausea Questionnaire, which used to assess patterns of NVP. Results: The frequency and severity of nausea and vomiting have shown statistically significant improvement throughout the following up in the study and control group. Improvement in the overall symptoms was more revealed in the study group than the control groupPConclusion: Ginger drink as well as antiemetic agent is effective in relieving mild to moderate nausea and vomiting during the first trimester of pregnancy. Recommendation: Using ginger as antiemetic agent on relieving mild to moderate nausea and vomiting during the first trimester of pregnancy is recommended.