End-stage renal disease (ESRD) has become a public health concern worldwide as the total number of ESRD patients requiring renal replacement therapy has been growing dramatically. In Egypt, there is an increase in prevalence and incidence of ESRD exerting a great burden on the health system. Moreover, in Egypt there is insufficient information about the quality of nursing care of hemodialysis patients. The study aims to assess nurses' performances for patient undergoing hemodialysis. The study Question: what is the level of nurses performance for patient undergoing hemodialysis. Descriptive design was used in the current study. The present study was carried out in hemodialysis units in Port- Said general hospital, El-Mabara hospital and Port-Fouad general hospital in Port- Said city. The sample of this study consisted of all (fifty three) nurses who were assigned to provide direct care for patients undergoing hemodialysis. The data were collected using. Tool I:  demographic data, Tool II:  Nurses' practice sheet. Results:  (1.8%) of studied nurses have adequate (60 %+) performance related to nursing care for patients undergoing hemodialysis. Conclusion: Almost all nurses working in the hemodialysis units had total inadequate total performance. Recommended, Providing the working nurses with continuing education and in-service education training program about hemodialysis and its management including the standards of nursing care pre, during and post.