Background: Pre-eclampsia is a major complication of pregnancy, it is pregnancy-specific Condition, represents a major cause of morbidity and mortality in mother, fetus and infant in many parts of the world.  Aim: to assess the maternal and labor outcome in women with pre-eclampsia in El-takhasose hospital in damitta city. Subject and Methods: Study was carried out in the obstetric and gynecological departments in El-Takhasose hospital in Damitta city using a case control design. The sample constituted 140 women; the study subjects were divided into two equal groups of 70 parturient women each, as follows: Group A; the study group, who should have a definite medical diagnosis of pre-eclampia. Group B; normotensive women without preeclampsia. Data were collected using five tools devised specifically for the study. Results: Women in the study group had high incidence of preeclampsia among yang women; low education level and unregular antenatal care. Conclusion: The study find that, the incidence rate of preeclampsia decreased by regular antenatal visits and prevent fetal and maternal complications.