Objectives: The aim of this study was to examine the impact of nursing implications (educational program on their knowledge) for osteoporosis among menopausal women. Subject and Methods: The study was carried out in the rheumatic and rehabilitation outpatients' clinic at Mansoura University Hospital at Mansoura city using a quasi-experimental (pre & post test) design.  The subjects of the study were 120 menopausal women attending the rheumatic and rehabilitation outpatients' clinic at Mansoura University Hospital and being diagnosed as positive for osteoporosis.  Data were collected using one tools devised specifically for the study. Results: The results revealed that there was a significant improvement in the women' knowledge score about osteoporosis especially definition, causes, signs and symptom, risk factors, intervention, diagnosis and management meanwhile, the scores in the follow up (after 3 months) tend to decline. Conclusion: Educational program has a significant and improvement impact on the menopausal women's knowledge regarding osteoporosis that tends to decline with the progress of time. Recommendations: Further research is required to investigate the effect of counseling program for osteoporotic women on their quality of life.