Background:Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that greatly impacts all aspects of health-related quality of life, including physical, emotional, social and spiritual. Aim: This study aimed at assessing health needs and self-efficacy for rheumatoid arthritis patients.A descriptive research design was conducted. Setting: At rheumatology outpatient clinics at Port-Said general hospital and Port-Fouad general hospital which are affiliated to the Ministry of Health in Port-Said governorate.A convenient sampleof 50 adult rheumatoid arthritis patients was included in the study. Tools of data collection: Tool (1) A Structured Interview consisted of two parts- a) Socio-demographic characteristics and medical history-b) Health Needs Questionnaire. Tool (2)Arthritis Self-Efficacy Scale (ASES). Results: More than half of study patients have health needs. The highest needs are in relation to psychological needs; then physical needs; then educational needs. The lowest needs are in relation to social and spiritual needs. Also, most of patients have high self-efficacy and there is statistically significant negative relation between health needs of RA patients and their self-efficacy. Conclusion: More than half of RA patients have health needs, although most of them have high self-efficacy. The highest needs are in relation to psychological needs, then physical needs, then educational needs, while the lowest needs are in relation to social and spiritual needs. Recommendations: Further study for assessment of factors influencing health needs and self-efficacy of RA patients.