Background:  Cardiac catheterization is a procedure used to diagnose and treat various forms of heart and vascular disease. Aim: This study is aimed to assess the health needs for patients undergoing cardiac catheterization. Design: A descriptive research design was conducted in this study. Sample: A convenient sample of newly patients from both genders undergoing cardiac catheterization (68 patients) from the Cardiac Catheterization Unit at the General Port-Said Hospital in Port-Said City. Tools: A structure interview tool consists of four parts: a) Demographic data and Patients' medical history. b) Health needs pre cardiac catheterization. c) Health needs during cardiac catheterization. d) Health needs post cardiac catheterization. Results: The results revealed that there is a high statistically significant relation between total health needs before, during and after cardiac catheterization. Conclusion:  There was no statistically significant relation between patients needs before cardiac catheterization and their demographic characteristics as gender, hospital stay, education, job and social status, there was statistically significant relation between patients needs during cardiac catheterization and their demographic characteristics regarding to gender, job and social status, also there was statistically significant relation between patients' needs after cardiac catheterization and their demographic characteristics regarding to the hospital stay and social status. Recommendations: The study recommended that conducting educational and training program for nurses regarding care of patients undergoing cardiac catheterization.