Background: The safe management of needles, syringes and other sharps generated by non-clinical activities is an emerging issue for local councils. Aim: the aim of the present study was to evaluate effect of educational programs on the knowledge, attitude, and practice of type 1 diabetic patients about proper sharps disposal at home. Subjects and methods: a quasi-experimental design was utilized in this study. Setting: This study was conducted in four primary health care centers in Port-Said city. Sample: All diabetic patients with type 1 diabetes mellitus attending the prementioned setting in the period of three months were included in the study, total number were 100 patients.  Methods:  Data collected by using three tools. Tool 1: includes Socio-demographic Data and patient's knowledge of safe disposal of insulin syringe at home. Tool II: patient's attitude of safe disposal of insulin syringe at home. Tool III: patient's practices of safe disposal of insulin syringe at home. Results: The findings of the present study indicated an improvement of the patient's knowledge, attitude and practice in various areas of patients' in various areas of safe disposal of insulin syringe after program implementation, this improvement was highly statistically significant (p ≤ 0.01). Conclusion &Recommendations: from the results of the present study, it can have concluded that the implementation of health program for diabetic patients about safe disposal of insulin syringe at home showed a remarkable improvement of the patient's level of knowledge, practice and attitude, it can be recommended that, there are obvious needs for health programs offered on simple media to diabetic patients to minimize wastes hazards