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189012

PRAZIQUANTEL- INDUCED TRANSIENT HYPOTENSION, DEPRESSED RESPIRATION AND ALTERED ELECTOCARDIOGRAM (ECG).

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Last updated: 22 Jan 2023

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Abstract

A relaxant effect was achieved by praziquantel on the rat thoracic aortic strip preparations which might be of cholinergic nature.
Praziquantel produced an acetylcholine-like effect on the perfused rabbit's heart.
A transient hypotensive effect and respiratory depression and altered ECG were traced. These effects revealed the peripheral cholinergic effects of the drug.

DOI

10.21608/zjps.1992.189012

Authors

First Name

MOSTAFA

Last Name

ABD EL-AZIZ

MiddleName

-

Affiliation

Pharmacology Department, Faculty of Veterinary Medicine, Zagazig University, Egypt.

Email

-

City

-

Orcid

-

First Name

Sawsan

Last Name

El-Sheikh

MiddleName

-

Affiliation

Department of Pharmacology, Faculty of Vet. Medicine, Zagazig University

Email

sawsan.el-sheikh@yahoo.com

City

-

Orcid

-

First Name

Gamal

Last Name

Shams

MiddleName

-

Affiliation

Pharmacology Department, Faculty of Vet. Med., Zagazig University, Egypt

Email

gamal.shams@yahoo.com

City

-

Orcid

-

First Name

Hosny

Last Name

Abdel Fadil

MiddleName

-

Affiliation

Pharmacology Department, Faculty of Veterinary Medicine, Zagazig University, Egypt.

Email

hosny.abdel-fadil@yahoo.com

City

-

Orcid

-

First Name

A.F.

Last Name

ABDEL ALIM

MiddleName

-

Affiliation

Pharmacology Department, Faculty of Veterinary Medicine, Zagazig University, Egypt.

Email

a.f.abdel-alim@yahoo.com

City

-

Orcid

-

First Name

S.M.

Last Name

MALHAT

MiddleName

-

Affiliation

Pharmacology Department, Faculty of Veterinary Medicine, Zagazig University, Egypt.

Email

s.m.malhat@yahoo.com

City

-

Orcid

-

Volume

1

Article Issue

2

Related Issue

24778

Issue Date

1992-12-01

Receive Date

1992-08-12

Publish Date

1992-12-01

Page Start

103

Page End

119

Print ISSN

1110-5089

Online ISSN

2356-9786

Article File

ZJPS_Volume 1_Issue 2_Pages 103-119.pdf

PDF . 8.3MB

Link

https://zjps.journals.ekb.eg/article_189012.html

Detail API

https://zjps.journals.ekb.eg/service?article_code=189012

Order

3

Type

Original Article

Type Code

862

Publication Type

Journal

Publication Title

Zagazig Journal of Pharmaceutical Sciences

Publication Link

https://zjps.journals.ekb.eg/

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Article

Created At

22 Jan 2023