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188998

SYNTHESIS AND PRELIMINARY TESTING OF SOME ANTHRANILIC ACID DERIVATIVES AS ANTIINFLAMMATORY, ANALGESIC AND ANTIPYRETIC AGENTS

Article

Last updated: 22 Jan 2023

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Abstract

A series of N - 3 - chloro -N- substituted phenyl -2- maleimidyl  anthranilic acid and its methyl ester were prepared. The reaction of either IV or V with potassium thiocyanate afforded quinazolinone thione derivatives. four of the prepared new compounds were screened pharmacologically for their antiinflammatory, analgesic and antipyretic properties.

DOI

10.21608/zjps.1993.188998

Authors

First Name

Mansour

Last Name

Abou-Kull

MiddleName

-

Affiliation

Medicinal Chemistry Department, Faculty of Pharmacy, University of Zagazig, Zagazig, Egypt

Email

meabou-kull@pharmacy.zu.edu.eg

City

-

Orcid

-

First Name

Sayed

Last Name

Lashine

MiddleName

-

Affiliation

Pharmaceutical Chemistry Department, Faculty of Pharmacy, Zagazig University, Egypt

Email

smlashine@pharmacy.zu.edu.eg

City

-

Orcid

-

First Name

Abdalla

Last Name

El-Shanawani

MiddleName

-

Affiliation

Department of Medicinal Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.

Email

aael-shanawani@pharmacy.zu.edu.eg

City

-

Orcid

-

First Name

Nageh

Last Name

Abou Taleb

MiddleName

-

Affiliation

FACULTY OF PHARMACY, CAIRO UNIVERSITY

Email

nageh.abou-taleb@yahoo.com

City

-

Orcid

-

First Name

Magdy

Last Name

Amer

MiddleName

-

Affiliation

Department of Pharmacology, Faculty of Veterinary Medicine, University of Mansoura, Egypt.

Email

magdy.amer@yahoo.com

City

-

Orcid

-

Volume

2

Article Issue

1

Related Issue

24775

Issue Date

1993-06-01

Receive Date

1993-04-01

Publish Date

1993-06-01

Page Start

140

Page End

149

Print ISSN

1110-5089

Online ISSN

2356-9786

Article File

ZJPS_Volume 2_Issue 1_Pages 140-149.pdf

PDF . 4.6MB

Link

https://zjps.journals.ekb.eg/article_188998.html

Detail API

https://zjps.journals.ekb.eg/service?article_code=188998

Order

14

Type

Original Article

Type Code

862

Publication Type

Journal

Publication Title

Zagazig Journal of Pharmaceutical Sciences

Publication Link

https://zjps.journals.ekb.eg/

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Article

Created At

22 Jan 2023