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186590

SYNTHESIS OF NEW THIENO-[2,3-b]-PYRIDINE AND PYRAZOLO-5,4-b-PYRIDINE DERIVATIVES

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Last updated: 04 Jan 2025

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Abstract

3-Cyano-4,6-dimethyl-2-pyridinethiol 1 was allowed to react with chloroacetone and hydrazine hydrate to give the corresponding thienopyridine derivative 2 and pyrazolopyridine derivative 5, respectively. Compound 2 reacted with aldehydes to yield 3a-3c. Reaction of compound 5 with thionyl chloride and arylidinemalononitriles gives 6 and 8a,b, respectively. Compound 6 reacted with benzil and p,p-dichlorobenzil to yield the corresponding benzilimine derivatives 7a,b.

DOI

10.21608/zjps.1994.186590

Authors

First Name

Gamal

Last Name

Ahmed

MiddleName

-

Affiliation

Chemistry Department, Faculty of Science, Zagazig University, Egypt.

Email

gamal.ahmed@yahoo.com

City

-

Orcid

-

Volume

3

Article Issue

2

Related Issue

24774

Issue Date

1994-12-01

Receive Date

1994-10-01

Publish Date

1994-12-01

Page Start

148

Page End

152

Print ISSN

1110-5089

Online ISSN

2356-9786

Article File

ZJPS_Volume 3_Issue 2_Pages 148-152.pdf

PDF . 1.5MB

Link

https://zjps.journals.ekb.eg/article_186590.html

Detail API

https://zjps.journals.ekb.eg/service?article_code=186590

Order

17

Type

Original Article

Type Code

862

Publication Type

Journal

Publication Title

Zagazig Journal of Pharmaceutical Sciences

Publication Link

https://zjps.journals.ekb.eg/

MainTitle

SYNTHESIS OF NEW THIENO-[2,3-b]-PYRIDINE AND PYRAZOLO-5,4-b-PYRIDINE DERIVATIVES

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Article

Created At

22 Jan 2023