Beta
ManageSearchChatDiscover
186441

USE OF CERTAIN METAL IONS FOR THE DETERMINATION OF INDOMETHACIN

Article

Last updated: 22 Jan 2023

OverviewSimilar Items

Subjects

-

Tags

-

Abstract

A simple and accurate method was described for the quantitative determination of indomethacin using Ag+ and Cu2+ ions. Indomethacin was precipitated from its neutral alcoholic solution by standard solutions of silver nitrate and copper acetate followed by determining the resulted slats using atomic absorption spectroscopy and colorimetric techniques. The optimum conditions for silver and copper indomethacin slat formations have been carefully studied. The molar ratio of the reactants in the case of copper was ascertained by atomic absorption spectroscopy and by formation of copper sodium diethyldithiocarbamate and was found to be 2:1 (indomethacin: cu+2). Both of the developed methods were compared with the previous official methods to indicate high accuracy (t-test) and reproducibility (f-test).

DOI

10.21608/zjps.1994.186441

Authors

First Name

Magda

Last Name

Ayad

MiddleName

-

Affiliation

Analytical Chemistry Department, Faculty of Pharmacy, Zagazig University. Zagazig. Egypt.

Email

mmayad@pharmacy.zu.edu.eg

City

-

Orcid

-

First Name

Hanaa

Last Name

Saleh

MiddleName

-

Affiliation

Department of Analytical Chemistry, Faculty of Pharmacy, University of Zagazig, Egypt.

Email

hisaleh@pharmacy.zu.edu.eg

City

-

Orcid

-

First Name

Sobhy

Last Name

El-Adl

MiddleName

-

Affiliation

Department of Medicinal Chemistry, Faculty of Pharmacy, Zagazige University, Zagazig, Egypt

Email

smel-adl@pharmacy.zu.edu.eg

City

-

Orcid

-

First Name

Nagla

Last Name

El-Kousy

MiddleName

-

Affiliation

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Zagazig, Egypt.

Email

nagla.el-kousy@yahoo.com

City

-

Orcid

-

First Name

Elham

Last Name

Taha

MiddleName

-

Affiliation

National Organization for Drug Control and Research, Giza, Egypt.

Email

elham.taha@yahoo.com

City

-

Orcid

-

Volume

3

Article Issue

2

Related Issue

24774

Issue Date

1994-12-01

Receive Date

1994-06-30

Publish Date

1994-12-01

Page Start

32

Page End

39

Print ISSN

1110-5089

Online ISSN

2356-9786

Article File

ZJPS_Volume 3_Issue 2_Pages 32-39.pdf

PDF . 3.2MB

Link

https://zjps.journals.ekb.eg/article_186441.html

Detail API

https://zjps.journals.ekb.eg/service?article_code=186441

Order

4

Type

Original Article

Type Code

862

Publication Type

Journal

Publication Title

Zagazig Journal of Pharmaceutical Sciences

Publication Link

https://zjps.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023