185079

HALOTHANE AND ISOFLURANE IN INTRALIPID AS INTRAVENOUS ANAESTHETICS TOo DOCS

Article

Last updated: 04 Jan 2025

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Abstract

Halothane 5% (0.6 ml/kg) and isoflurane 10% (0.4 ml/kg) in intralipid injected intravenously over one minute were the minimum doses that consistently abolished movement in response to tail clamping in dogs. The depth of anaesthesia was controlled by adjusting the infusion rate. Blood pressure decreased during induction and regained progressively during maintenance with low doses especially with isoflurane. The heart and respiratory rates were increased during maintenance with low doses while a decrease was observed by increasing the depth of anaesthesia that was more prominent with halothane. Recovery achieved after infusion of halothane 5% or isoflurane 10% for 30 minutes, was fast and survivors behaved normally. Lung tissues were macro and microscopically normal. It was concluded that, intravenous administration of halothane 5% or isoflurane 10% induced ultra short general anaesthetic effect and had a safe hemodynamic and respiratory responses especially with isoflurane.

DOI

10.21608/zjps.1996.185079

Authors

First Name

M.A

Last Name

Rifky

MiddleName

-

Affiliation

Anaesthesiology Dept. Faculty of Med., Zagazig University, Egypt

Email

m.a.rifky@yahoo.com

City

-

Orcid

-

First Name

M.H.

Last Name

Khairry

MiddleName

-

Affiliation

Pharmacology Dept. Faculty of Vet. Med, Zagazig University, Egypt

Email

m.h.khairry@yahoo.com

City

-

Orcid

-

First Name

S.M.

Last Name

Abd-El-Samee

MiddleName

-

Affiliation

Anaesthesiology Dept. Faculty of Med., Zagazig University, Egypt

Email

s.m.abd-el-samee@yahoo.com

City

-

Orcid

-

First Name

F. D.

Last Name

El-Sedawy

MiddleName

-

Affiliation

Animal surgery Dept. Faculty of Vet. Med, Zagazig University, Egypt

Email

f.d.el-sedawy@yahoo.com

City

-

Orcid

-

Volume

5

Article Issue

1

Related Issue

24769

Issue Date

1996-06-01

Receive Date

1996-04-17

Publish Date

1996-06-01

Page Start

132

Page End

137

Print ISSN

1110-5089

Online ISSN

2356-9786

Link

https://zjps.journals.ekb.eg/article_185079.html

Detail API

https://zjps.journals.ekb.eg/service?article_code=185079

Order

20

Type

Original Article

Type Code

862

Publication Type

Journal

Publication Title

Zagazig Journal of Pharmaceutical Sciences

Publication Link

https://zjps.journals.ekb.eg/

MainTitle

HALOTHANE AND ISOFLURANE IN INTRALIPID AS INTRAVENOUS ANAESTHETICS TOo DOCS

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Article

Created At

22 Jan 2023